Dr. Isha Khaitan, K18218, Dr. Thakkar Hansa Harshadbhai, Dr. Palak Macwana
Purpose : To narrow the differential diagnosis and establish the role of ophthalmic ultrasonography in leukocoria.
Method : In this prospective study 150 patients with leukocoria were included. Apart from detailed history and ophthalmic physical examination, all patients were subjected to B-scan ultrasound (10 MHz)
Results : Amongst 300 eyes, 219 eyes were affected. Fifty-two eyes had retinoblastoma. Calcification detection rate was 65.38% on ophthalmoscopy 98% on ultrasonography. Ophthalmoscopic evaluation was not possible in 51 eyes which were diagnosed on ultrasonography. The study revealed congenital cataract 31.96% followed by retinoblastoma 23.74%, retinopathy of prematurity 11.42% and traumatic cataract 6.85%
Conclusion : Ultrasonography is an indispensable tool for both screening and accurate diagnosis of leukocoria. It facilitates in cases with significant media opacity and early detection of malignant tumor, thereby helping in deciding appropriate treatment protocol for the patients

