Dr. Aditi S Parikh, Dr. Roopashri Matada, Dr. Vinay R Murthy,Dr. Shwetha Nc
Purpose:To evaluate the efficacy and safety of Accelerated Corneal collagen cross-linking (CXL) with Riboflavin for Progressive Keratoconus by change in visual acuity, scheimpflug imaging and specular microscopy.
Method:40 eyes of 24 patients with progressive keratoconus(stages 1-2, Amsler-Krumeich classification) underwent Accelerated CXL with 20min of Riboflavin(0.1%) soak followed by 10min of UV-A light exposure at irradiance of 9mW/cm2. Pre-operative measured parameters were repeated 1, 3, and 6 months post-operatively.
Results:At 6 months, a significant improvement in mean logMAR BCVA(p<0.001) and keratometry readings(p<0.05) was found. Decrease in pachymetry values(p<0.001), lead to increase in average progression index. Anterior stromal haze remained in 27.5%. No noticeable change in refractive map indices, endothelial count or intraocular pressure.
Conclusion:Accelerated CXL is safe measure to increase stability of cornea and halt the progression in mild to moderate keratoconus