Dr. Ruchi Pherwani, P17407, Dr. Mehul Ashvin Kumar Shah, Dr. Dilipkumar Batra, Dr. Kashyap Patel
Aim: To study the relationship between visual outcome and the photoreceptor inner segment/outer segment (IS/OS) layer in patients with macular edema.
Methods: Cross sectional study of patients with macular edema. SD OCT was done in patients pre and post anti-VEGF or IVTA. The IS/OS ratio was calculated & data were analyzed statistically.
Results: 48 eyes: 21 male and 27 female; median age, 58.50 ± 10.8 years).27 eyes had cystoid macular edema, 10 eyes had diffuse macular edema. The median central subfield thickness was 462 ± 150.3 μm. 8 (16.7%), 11 (22.9%), and 29 (60.4%) eyes had venous tributary occlusion, Pseudophakic macular edema & diabetic macular edema respectively. Significant difference between pre- and post-treatment vision (p = 0.001); pre and post treatment IS, OS, and IS/OS ratio (p = 0.000) seen.The initial BCVa differed significantly as per IS/OS ratio (p = 0.01).
Conclusion: IS/OS ratio is not significantly correlated with final BCVA after treatment for macular edema.