Dr. Dipankar Das, D08987, Dr. Harsha Bhattacharjee, Dr. Satyen Deka, Dr. Ronel Soibam
Retinal pigment epithelial (RPE) changes in pathology are challenging for ophthalmologists and basic science scientists. We studied the pattern of atrophy in RPE in pathological samples.
Methods: Observation and laboratory study in (n=18) enucleated eyeball samples of traumatic / painful blind eye. RPE were studied in those samples unstained and with different types of stainings. They were documented in grossing (LEICA 6SD) and in compound microscope ( Axioskop MRC, Zeiss). Pattern of RPE atrophy correlated with underlying choroidal vascular patterns.
Results: Pattern of RPE atrophy showed central cell in the cluster were first to be affected compared to the adjoining cells. Size of inner cells were seen larger and correlated with rest of the cells. These cells forms a rosette which stand alone and can act as a anatomical unit.
Conclusion: Morphological cellular changes in RPE found to be unique and can have a clinical significance.