Dr. Sunita Chaurasia, C13848, Dr. Muralidhar Ramappa
Background: Endothelial disorders cause alterations in the Descemet’s membrane (DM). HR-OCT has a resolution of 5 microns and hence can aid in characterizing of posterior membrane abnormalities better.
Methods: HR-OCT was performed in various endothelial diseases such as Fuchs, Posterior polymorphous corneal dystrophy(PPCD), and Congenital Hereditary Endothelial dystrophy. The characteristic changes at the posterior membrane level were compared with normal subjects.
Results: The DM-endothelial complex was thickened in advanced cases of Fuchs Endothelial dystrophy. In eyes with PPCD presenting with significant corneal edema, a double reflective membrane was seen at the level of Descemet’s membrane plane.
Conclusions: HR-OCT helps in ascertaining the DM alterations in endothelial diseases with corneal edema. The pattern of posterior membrane abnormality can aid in making a proper differential diagnosis in advanced cases presenting with corneal edema