Dr. Himanto Nath Hazarika, H06877, Dr. Dipak Bhuyan, Dr. Suranjana Chaliha Hazarika, Dr. Renu S. Patil
Aim:To treat a case of Mycotic Corneal Ulcer following penetrating keratoplasty(PK).
Method:A 6 month old post PK patient, presented with discomfort,watering,mild pain and white corneal opacity in RE for 6 days.VA- PL +ve. SLE showed central corneal epithelial defect with peripheral graft edema,stromal infiltrate,loose suture at 5 o’clock,circum-corneal congestion and AC hypopyon. Lab/Ex. revealed fungal elements.Topical steroids stopped temporarily.Topical 5% natamycin,fluconazole 200 mg BD,antibiotic and atropine drops started. At 5th day slight improvement of corneal ulcer but increase in hypopyon noted. AC paracenetesis with intracameral 10µgm of AmphotericinB in 0.1ml given and aspirate sent for C/S.
Results:Clinical response noted after 1 week with no recurrence of hypopyon.1 month follow up-ulcer healed with quiet eye,with macular corneal opacity(graft rejection).
Conclusion:I/C AmphotericinB is a useful modality in severe keratomycosis not responding to topical natamycin alone