Dr. Sushant Madaan, M18445, Dr. Swati Tomar
Purpose: To analyze mean corneal spherical aberration(CSA) and its co-relation with age in Indian population using pentacam
Methods:300 eyes of 180 subjects,aged 10-80 years with matched refractive errors,divided into 3 groups according to age.Spherical aberration (SA) were measured using pentacam HR (OCULUS) at the 6-mm optical zone.
Results:Mean CSA of 4th order of the whole group was 0.236048 ± 0.2416 µm.RMS CSA of 10 – 25 years was 0.17231 ± 0.1087 µm, RMS CSA of 25 -50 years was 0.21321 ±0.18103 µm, 50-80 years old have a RMS CSA of 0.39447 ± 0.4110 µm (P < 0.002).Positive correlation was found between total CSA and age (r=0.359558, P=0.003)and 4th order spherical aberration and age (r = 0.354795, P < 0.002).The variation in 6th order CSA was quite less with age (r=0.032524, P=0.763).Fourth order aberrations constitute 30.20% of the HOA.
Conclusion:Total CSA and 4th order CSA increases significantly with age while 6th order CSA variation with age is insignificant statistically

